Uso de cocaína e seus efeitos no sistema nervoso
DOI:
https://doi.org/10.51247/st.v8i3.573Palavras-chave:
Cocaína, sistema nervoso central, neurotransmissão, dependência, neurotoxicidade.Resumo
O presente estudo tem como objetivo analisar os efeitos do consumo de cocaína no sistema nervoso central (SNC), focando no seu impacto na neurotransmissão e nas estruturas cerebrais. Foi utilizada metodologia de revisão bibliográfica exaustiva, baseada em bases de dados científicas como PubMed, Scopus e SciELO, priorizando estudos dos últimos cinco anos. As principais descobertas indicam que a cocaína bloqueia a recaptação de neurotransmissores essenciais como a dopamina, a serotonina e a noradrenalina, gerando hiperativação neuronal associada à dependência, ao comprometimento cognitivo e à neurotoxicidade. Os resultados mostram que o consumo crónico afeta o córtex pré-frontal, o hipocampo e o sistema límbico, aumentando o risco de doenças psiquiátricas e neurodegenerativas, bem como de complicações cardiovasculares. Como aplicações, o estudo destaca a necessidade de intervenções terapêuticas multidisciplinares, incluindo abordagens farmacológicas e reabilitação cognitiva. Conclui-se que a cocaína tem um impacto multissistêmico que requer estratégias de prevenção e tratamento mais eficazes, bem como maior investimento em pesquisas neurocientíficas para mitigar seus efeitos na saúde pública.
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Direitos de Autor (c) 2025 Yanetzi Loimig Arteaga-Yanez
Este trabalho encontra-se publicado com a Licença Internacional Creative Commons Atribuição-NãoComercial-CompartilhaIgual 4.0.
